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  • [外文期刊] Garside D Hargrove RL Winecker RE 《Journal of Analytical Toxicology》, ISTIC EI SCI PKU CSSCI 2009 3
    Oxymorphone, a semi-synthetic opioid analgesic, has been available as Numorphan((R)) since the 1950s in the form of injectable solutions and a suppository. Recently, in 2006, oxymorphone was approved b...
    OxymorphonemgAutopsyConcentrationIn Blood羟吗啡酮尸体解剖
  • [外文期刊] Peniston JH Gould E 《Clinical therapeutics》, ISTIC EI SCI PKU CSSCI 2009 2
    OBJECTIVE: This study assessed the potential effects of age, sex, and prior opioid use on the response to oxymorphone extended release (ER) in patients with moderate to severe chronic low back pain. ME...
    OxymorphoneOpioidsEstrogen ReceptorsAgeNOSPlacebos羟吗啡酮安慰剂
  • [外文期刊] Gould EM Jensen MP Victor TW Gammaitoni AR White RE Galer BS 《The clinical journal of pain》, ISTIC EI SCI PKU CSSCI 2009 2
    OBJECTIVE: In controlled trials of analgesics, the primary outcome variable is most often a measure of global pain intensity. However, because pain is associated with a variety of pain sensations, the ...
    PainOxymorphoneEstrogen ReceptorsAnalgesicstherapeutic aspects疼痛羟吗啡酮镇痛药
  • [外文期刊] Cone EJ Caplan YH Moser F Robert T Black D 《Journal of Analytical Toxicology》, ISTIC EI SCI PKU CSSCI 2008 4
    A minor pathway for the biotransformation of morphine to hydromorphone has been identified in humans. Recently, an unsubstantiated claim that morphine is metabolized to hydromorphone and then to oxymor...
    MorphineHydromorphoneOxymorphoneng吗啡氢吗啡酮羟吗啡酮
  • [外文期刊] Shuey DL Gudi R Krsmanovic L Gerson RJ 《Toxicological sciences: An official journal of the Society of Toxicology》, ISTIC EI SCI PKU CSSCI 2007 2
    Oxymorphone is a potent opioid analgesic. Oral administration of oxymorphone to rats at doses >or= 20 mg/kg and mice at 500 mg/kg produced an increase in micronucleated polychromatic erythrocytes (M...
    OxymorphoneSodium SalicylateBody TemperatureOralincidence of cases羟吗啡酮水杨酸钠体温
  • [外文期刊] Shuey DL Woodland C Tremblay C Gregson R Gerson RJ 《Toxicological sciences: An official journal of the Society of Toxicology》, ISTIC EI SCI PKU CSSCI 2007 1
    Despite their long history of chronic use, little information is available regarding the carcinogenicity of opioid analgesics. Oxymorphone is a potent morphinan-type mu-opioid analgesic used for treatm...
    AnalgesicsOpioidCarcinogensOxymorphone镇痛药阿片类致癌物羟吗啡酮
  • [外文期刊] Gimbel JS 《Drugs of today: Medicamentos de actualidad》, ISTIC EI SCI PKU CSSCI 2008 10
    The undertreatment of acute and chronic pain continues to be a significant health concern in the U.S. Opioids are recommended for the treatment of acute or chronic pain of moderate to severe intensity ...
    OpioidsOxymorphoneDischarge (release)MoleculeOral羟吗啡酮
  • [外文期刊] Neuvonen M Neuvonen PJ 《Therapeutic Drug Monitoring》, ISTIC EI SCI PKU CSSCI 2008 3
    A sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of oxycodone, noroxycodone, oxymorphone, and noroxymorphone....
    OxycodonenoroxycodoneMorphine SulfatePlasmaOxymorphone羟可酮血浆羟吗啡酮
  • [外文期刊] Scott G. McKinley J. Jacob Snyder Eric Welsh Charles M. Kazarian Matthew H. Jamerson Kevin L. Klette 《Journal of Analytical Toxicology》, ISTIC EI SCI PKU CSSCI 2007 8
    Human urine specimens that were determined to be presumptively positive for oxycodone and its metabolite, oxymorphone, by immunoassay screening were assayed using fast gas chromatography-mass spectrome...
    OxymorphoneOxycodoneFastUrinary羟吗啡酮羟可酮
  • [外文期刊] Ahdieh H White R 《The annals of pharmacotherapy》, ISTIC EI SCI PKU CSSCI 2007 12
    We read with interest Chamberlin et al.review of oral oxymorphone. Although we agree with the authors' main conclusions that oxymorphone has efficacy and tolerability similar to that of other opioids, ...
    CommentOralOxymorphonePain management羟吗啡酮
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