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Device (1), and method for manufacturing the same, for detecting the growth of a three-dimensional cell cluster (C), comprising: a substrate (2) having a support surface (21); a plurality of electrodes (3) arranged according to a predetermined spatial distribution, for detecting an electrical potential in the presence of a three-dimensional cell cluster (C); a plurality of three-dimensional scaffolds (4), comprising at least a first scaffold (41), arranged at a respective measuring electrode (31), and at least a second scaffold (42), arranged at a respective reference electrode (32), wherein the at least one first scaffold (41) has a proliferation conformation, adapted to promote the growth of the three-dimensional cell cluster (C), and the at least one second scaffold (42) has an inhibition conformation adapted to prevent the growth of the three- dimensional cell cluster (C).

Chip device (10) for an organ-on-a chip (OOC), comprising: - a chip (20) comprising a culture chamber (22) for housing a cellular structure; - a pressure generating system for exerting a compression action upon the cellular structure housed in the culture chamber (22); wherein the pressure generating system comprises: - a chamber body (40) having a pressure chamber (42); - a membrane (80) having a first side (82) facing the culture chamber (22) and a second side (84) facing the pressure chamber (42), - a pressure generator (90) for supplying a work fluid to the pressure chamber (22) and building a pressure in the pressure chamber (22) that moves said membrane in the direction of the culture chamber (22) to execute a compression action upon the cellular structure contained therein. The chip device is characterized in that it comprises a support element (60) supporting the membrane (80), which is arranged between the chip (20) and the chamber body (40) of the pressure generating system.

本申请公开了一种荧光PCR仪用避光样本架，包括基板，所述基板通过角度调节结构与盒体相连，所述角度调节结构用于驱动并锁定所述盒体相对于基板的倾斜角度；本申请通过角度调节结构，用户可将样本架调整至最舒适的观察和操作角度，显著减轻工作疲劳，提升操作精准度；通过多个独立的腔体和放置板设计，允许对样本进行物理隔离和分类管理，有效防止交叉污染和样本混淆；通过导向锁紧结构确保了放置板推拉顺滑，定位精准；其内置的弹簧提供了向下的助力，将放置板和遮光罩组件锁紧在盒体内；通过遮光罩组件的设置，能够在抽出放置板时，对放置板的侧面进行遮光，遮光效果好。

Task: Provide a culture apparatus that suppresses fluctuations in drug solution concentration and enables standardized culture under a uniform temperature environment in atropine derivative-induced fibroblast culture. Solution means: A bottom sealing plate 2 is connected to an open end of a culture chamber body 1 to form a sealed culture space, and cell culture dishes 4 are placed on a culture support stand 3 above it. Atropine drug solution is gravitationally transported from a reservoir bottle 5 outside the culture chamber body 1 through a transport passage via a check valve. Volatile atropine is condensed by a condensation plate 7 inside an evaporation recovery cover 6 positioned above the top of the culture chamber body 1 and returned to the reservoir bottle 5 through a guide pipe 8. The winding density of electric heating wires embedded in the inner layer of the side wall is gradually reduced from the bottom to the top, and a heat insulating layer is filled between the outer wall and the inner layer to compensate for vertical temperature gradients. The connection portion with the bottom sealing plate 2 is sealed using a sealing ring 9 and a pressing ring 10. Stabilization of drug solution concentration and standardization of culture conditions are achieved by condensing and recovering volatile drug solution and equalizing temperature. Selected figure: Figure 1

The present invention relates to a cartridge and an analyte testing apparatus including the same. Specifically, according to one embodiment of the present invention, a cartridge and an analyte testing apparatus including the same can be provided, comprising: a plurality of testing chambers providing a space for containing a reaction liquid; a supply channel providing a passage for the reaction liquid supplied from the outside to flow into the plurality of testing chambers; and a plurality of resistance channels through which the reaction liquid discharged from the plurality of testing chambers flows, wherein the plurality of resistance channels are each connected to the plurality of testing chambers so as to discharge gas in the plurality of testing chambers to the outside, and a second resistance value, which is the sum of the resistance values of the plurality of resistance channels, is greater than a first resistance value, which is the sum of the resistance values of the supply channel and the plurality of testing chambers.

Compositions and/or methods for growing biological material are generally described. In certain embodiments, an emulsion having an aqueous fluid and a non-aqueous fluid is described. The non-aqueous fluid may have greater wettability than the aqueous fluid, which may be advantageous for preventing biofouling, for example. The aqueous fluid may comprise a biological material, and the non-aqueous domain may comprise a compound. The compound may be capable of exiting the non-aqueous fluid and entering the aqueous fluid, where the compound may be at least partially consumed by the biological material. The compound entering the aqueous fluid may benefit the biological material (e.g., increase growth rate).

本实用新型涉及一种应用于生物指示剂爆破夹，属于爆破夹技术领域，包括上压夹和下承载夹，上压夹与下承载夹铰接，下承载夹设有凸块，凸块上设有装载孔，装载孔用于装载并定位生物指示剂，装载孔呈阶梯状，装载孔下部呈锥形，以适配不同型号的生物指示剂；上压夹设有下压槽，生物指示剂在下压槽内活动；本实用新型所述的应用于生物指示剂爆破夹，通过上压夹的下压槽设计，使本装置无需大角度开合，方便抓握使力；下承载夹的装载孔下部呈锥形，可适配不同型号的生物指示剂；本实用新型结构简单，操作便捷省力，同时满足不同型号的生物指示剂的爆破。

本实用新型涉及发酵罐技术领域，且公开了一种发酵罐补碱装置，包括罐体和安装在罐体一侧的补液桶，罐体内设有喷洒组件，罐体的顶部连接有输液组件，输液组件的两端分别与喷洒组件和补液桶连通。该种发酵罐补碱装置，通过输液组件将补液桶中的碱液输送至喷洒组件，并利用喷洒组件将碱液均匀喷洒到罐体内，可有效避免因碱液集中添加导致的剧烈中和反应，提升碱液分散的均匀性，从而增强罐体内环境的稳定性。

[Problem] To provide a low-cost replacement device for microbial culture that offers good workability during replacement, reduces the workload on the operator. [Solution] The replacement device 2 functions as a replacement device for microbial culture that is detachably installed on the main body of the device for culturing the target microorganism. It comprises a culture vessel 31 for culturing the target microorganism, a culture medium container 21 that stores consumables (culture medium B) to be replenished in liquid form in the culture vessel 31, and a connecting part 40 and a silicone tube 33 for supplying the culture medium B from the culture medium container 21 to the culture vessel 31, all of which are pre-sterilized by gamma rays. [Selected Figure] Figure 3

本申请涉及基因测序领域，旨在解决已知技术测序耗时长、成本高的问题，提供测序芯片及测序装置。其中，测序芯片包括基层和盖层。基层包括基底。基底具有相背的第一表面和第二表面；第一表面具有测序区；基底开设有进液孔和出液孔。盖层叠设于基层的第一表面一侧；盖层和测序区之间限定测序流道；测序流道连通于进液孔和出液孔之间。本申请的有益效果是测序效率高、测序成本较低。