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动物疾病（英文）
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2026年2期
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Climate change and AMR in animal diseases:a one health perspective on emerging global risks
Climate change and AMR in animal diseases:a one health perspective on emerging global risks
摘要
Introduction
The convergence of anthropogenic climate change,the escalating antimicrobial resistance(AMR)crisis,and the unabated emergence of zoonotic infections represents a profound planetary health challenge of the twenty-first century(GBD 2021 Antimicrobial Resistance Collabora-tors 2021;Mora et al.2022).While antibiotic exposure is widely recognized as the primary selection pressure for AMR,recent large-scale genomic evidence suggests that global warming and hydrological extremes may act as macro-environmental contributors that challenge the ecological barriers containing resistant pathogens(Zhou et al.2026).This editorial integrates these intersecting crises through the One Health conceptual framework,utilizing non-typhoidal Salmonella(NTS),a ubiquitous zoonotic pathogen bridging agricultural,environmental,and human host interfaces,as a sentinel model system.We delineate how micro-evolutionary pathoadaptive mechanisms might facilitate pathogen persistence within intensive production systems,and how macro-genomic analyses reveal that climate variables are significantly associated with an estimated 10％increase in the global AMR baseline.Crucially,we propose a tripartite govern-ance framework combining climate-informed genomic surveillance,targeted animal health interventions,and integrated cross-sectoral policies to mitigate this emerg-ing systemic risk.
年，卷(期)：
2026, 6(2)
机标分类号：
S
F270.7
P208
在线出版日期：
2026年8月19日
