上皮性卵巢癌治疗进展及热点问题
Advances and hot topics in the treatment of epithelial ovarian cancer
摘要
上皮性卵巢癌仍是致死率最高的妇科恶性肿瘤，尽管面临诸多挑战，但其诊疗发展正以前所未有的速度不断突破。本文聚焦上皮性卵巢癌，紧扣当前临床决策的四大热点展开系统性述评：初始策略优化选择、一线维持治疗困境突破、二次减瘤手术的价值再评估、铂耐药复发治疗策略的最新证据。通过对上述热点问题的梳理与探讨，该文旨在为临床诊疗路径优化与未来研究方向的确立提供理论参考，从而助力上皮性卵巢癌整体诊疗水平向精准化、个体化的方向持续提升。
Epithelial ovarian cancer (EOC) remains the gynecological malignancy with the highest mortality rate. Despite numerous challenges, breakthroughs in its treatment are being achieved at an unprecedented pace. This article focuses on EOC and provides reviews and discussions centered around four current clinical decision-making hot-spots: optimization of initial treatment strategies, breakthroughs in the dilemma of first-line maintenance therapy, re-evaluation of the secondary cytoreductive surgery, and the latest evidence on strategies for platinum-resistant recurrence. By discussing these key issues, we aim to provide a theoretical reference for optimizing clinical strategies and promising avenues for future study, thereby contributing to the continuous advancement of precision and individualized care in the management of epithelial ovarian cancer. Thereby continuously improving the overall precision and individualization of epithelial ovarian cancer management.
年，卷(期)：
2026, 106(40)
在线出版日期：
2026年11月3日
